ABSTRACT
@#Introduction: Dengue fever is caused by the dengue virus that is transmitted via Aedes mosquitoes. The lifecycle of Aedes mosquitoes is affected by the local climate (rainfall) which influences dengue transmission. Sabah is one of the states that is laden with a high incidence rate of dengue in Malaysia and the condition seems to have worsened with sudden, multiple outbreaks occurring in the year 2016. Methods: An ecological analysis was conducted in Keningau, Sabah to analyse dengue case patterns and distribution over a 5-year period and to exhibit the correlation between rainfall, larval indices, dengue incidences, and outbreaks. Results: Significant cross-correlation analysis (CCF) was discovered between rainfall and Aedes index at lag number 5 with a correlation coefficient of 0.151 (±0.063) as well as between rainfall and Breteau Index at lag number 5 with a correlation coefficient of 0.143 (±0.063). However, no significant cross-correlation analysis was found between Aedes index and dengue incidences. Associations were also seen between larval indices and outbreak cases. Conclusion: This study showed an increase of Aedes and Breteau Indices to susceptibility level five weeks after rainfall which increases the risk of dengue transmission.
ABSTRACT
@#Strongyloides stercoralis is an intestinal helminth that infects humans through contact with soil containing the larvae. Methods A systematic search was performed for relevant titles, abstract and keywords in database from Cochrane Library, PLOS One, PubMed and several other sources in October 2017 based on PICO strategy. Out of 511 papers that were evaluated for possible inclusion, final assessment for eligibility has yielded a total of 17 papers to be included which were found suitable for analysis covering period from 2012 till 2016. Results A major challenge of giving an overview of prevalence data for S. stercoralis lies in the low sensitivity of diagnostic method used which resulted in very low prevalence in certain countries. Cambodia and Laos presented with high prevalence ranging from 17.4% to 45.9% by using high sensitivity of diagnostic methods. The current prevalence situation of S. stercoralis in Southeast Asia still have wide gaps remains due to several reasons. Conclusions The information we have today only scratches the surface which cannot truly reflect the true burden of S. stercoralis in Southeast Asia The main risk factor is personal hygiene practices especially amongst males.